Piperafizine A is a methylated diketopiperazine formed by the condensation of phenylalanine, produced by a number of species in the Streptomyces genus. Piperafizine A exhibits little activity in vitro but potentiates vincristine antitumor potency.
Piperfizine A is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Piperfizine A is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
| Mechanism of Action | The mechanism of action has not been characterised. |
| Molecular Formula | C19H16N2O2 |
| References | Piperafizine A and B, potentiators of cytotoxicity to vincristine. Kamei, H. et al. , J. Antibiot., 1990, 43, 1018. |