SKU: P096  / 
    CAS Number: 58523-30-1

    Pseurotin A

    $117.50 - $409.00
    Pseurotin A
    • Detailed Description

      CAS Number: 58523-30-1

      Molecular Formula: C22H25NO8

      Molecular Weight: 431.4

      Mechanism of Action: Pseurotin A induces multipolar and branching neurites comparable to β-NGF, an endogenous neurotrophic factor.

      Storage Conditions: -20°C

    • Specifications

      Appearance: White solid

      Purity Level: >95% by HPLC

    • References

      References: Novel neuritogenic activities of pseurotin A and penicillic acid. Komagata D. et al. J Antibiot. 1996, 49, 958.

      Synerazol, a new antifungal antibiotic. Ando O. et al. J Antibiot. 1991, 44, 382.

      Pseurotin, a new metabolite of Pseudeurotium ovalis Stolk having an unusual hetero-spirocyclic system. Bloch P. et al. Helv. Chim. Acta 1976, 59, 133.

    Pseurotin A is a fungal metabolite with an unusual hetero-spirocyclic ring system. It has potent neuritogenic activity in PC12 phaechromocytoma cells, a useful model for adrenergic neuronal differentiation. Pseurotin A also exhibits chitinase inhibition and acts synergistically with azole antifungal agents.

    Pseurotin A is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number: 58523-30-1

    Molecular Formula: C22H25NO8

    Molecular Weight: 431.4

    Mechanism of Action: Pseurotin A induces multipolar and branching neurites comparable to β-NGF, an endogenous neurotrophic factor.

    Storage Conditions: -20°C

    Appearance: White solid

    Purity Level: >95% by HPLC

    References: Novel neuritogenic activities of pseurotin A and penicillic acid. Komagata D. et al. J Antibiot. 1996, 49, 958.

    Synerazol, a new antifungal antibiotic. Ando O. et al. J Antibiot. 1991, 44, 382.

    Pseurotin, a new metabolite of Pseudeurotium ovalis Stolk having an unusual hetero-spirocyclic system. Bloch P. et al. Helv. Chim. Acta 1976, 59, 133.