SKU: R029  / 
    CAS Number: 144860-68-4

    Reveromycin B

    $277.35 - $970.71
    Reveromycin B is an analogue of reveromycin A formed by rearrangement of the 6:6 spiroketal to a 5:6 spiroketal. Lacking much of the biological activity of reveromycin A, reveromycin B is a useful negative control in resolving the mode of action of this class.

    Reveromycin B is soluble in ethanol, methanol, DMF and DMSO.  
    ReferencesReveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. Takahashi H. et al. J. Antibiot. 1992, 45, 1414.

    Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. Miyamoto Y., et al. , J. Biol. Chem., 2002, 277, 28810.