Sartorypyrone B is a pentacyclic meroterpenoid metabolite isolated from Aspergillus (syn. Neosartorya) species. While
sartorypyrone B possesses no antibiotic activity against S. aureus, P. aeruginosa. B. subtilis and E. coli, it is nonethelesss
capable of selective potentiation of ciprofloxacin, ampicillin, oxacillin and cefotaxime against E. coli, S. aureus and E. fecium.
The mode of action of Sartorypyrone B is not understood at this time.
Eamvijarn A et al. et al (2013) Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahed. 8583.
Nelson M et al (2014) Antibacterial and antibiofilm activities of tryptoquivalines and meroditerpenes Isolated from the marine-derived fungi Neosartorya paulistensis, N. laciniosa, N. tsunodae, and the soil fungi N. fischeri and N. siamensis. Marine Drugs 12:822