Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
Click here for our cancer research digital flyer.
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has...
Mithramycin A was the first of the aureolic acid class of antitumor antibiotics, isolated from Streptomyces.Mithramycin A is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.Mechanism of ActionMithramycin inhibits transcription and...
Matrine is a natural alkaloid extracted from the Chinese herb Sophora flavescens. Matrine has demonstrated antiviral and anti-inflammatory bioactivity with relatively low toxicity. It has been used for cancer resarch and has been shown to...
Meleagrin is an alkaloid with antitumor and antibiotic activity, isolated from a number of species of Penicillium. Meleagrin is a common taxonomic marker for fungal contamination of foodstuffs. Note that meleagrin, the fungal metabolite, should not be...
Honokiol is a bioactive component of Magnolia obovata, known for its medicinal properties in traditional Asian medicine. Researchers have been interested in its promising antitumor activity, and have reported honokiol inducing apoptosis and inhibiting...
Kazusamycin B is a metabolite and minor member of the Leptomycin complex isolated from some Streptomyces species. It is a hydroxylated analog of Leptomycin A, a nuclear export inhibitor. It is similar to Leptomycins A and B in physico-chemical and...
Nogalamycin is an unusual anthracycline produced by Streptomyces nogalater var. nogalater, reported by researchers at Upjohn in 1965. Nogalamycin contains two saccharides: the neutral monosaccharide attaches to the D ring, similar to the aminoglycoside...
Neratinib Maleate is the maleate salt form of Neratinib. Neratinib is a quinoline derivative. It acts as a tyrosine kinase inhibitor and has anticancer properties. Neratinib has shown benefit for HER2 positive breast cancer and non-small cell...
Neratinib is a quinoline derivative. It acts as a tyrosine kinase inhibitor and has anticancer properties. Neratinib has shown benefit for HER2 positive breast cancer and non-small cell lung cancer.Mechanism of ActionNeratinib is a dual inhibitor...
Tipiracil is a member of the pyrimidone class. It inhibits the enzyme thymidine phosphorylase (TPase), which is an endothelial cell growth factor. It is used in combination with Trifluidine, since it inhibits the enzyme that metabolizes...
Steffimycin B is an anthracycline metabolite isolated from a Streptomyces sp. with antibacterial and antineoplastic properties. Crystallographic studies of binding to DNA suggest that it has a higher CpG base sequence specificity over the TpA step,...
Lenvatinib, the free base form of the compound, is a small-molecule multityrosine kinase inhibitor that inhibits many receptor tyrosine kinases including vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and stem cell factor...
