Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Luzopeptin A is a member of the echinomycin (quinomycin A) class of antitumor and antibiotic agents. Luzopeptin A is also a potent inhibitor of HIV-1 and HIV-2 reverse transcriptase. Luzopeptin A is soluble in DMF or DMSO. Moderately soluble...
Tetranactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp.. Unlike the other macrotetrolides, tetranactin exhibits potent insecticidal activity.Tetranactin is soluble in ethanol, methanol, DMF and DMSO.Mechanism of...
Pyoluteorin is a small chlorinated pyrrol produced by several species of Pseudomonas, first reported in 1958. Pyoluteorin has a broad bioprofile, demonstrating antibiotic, antifungal and herbicidal activity. More recently, Pyoluteorin has been...
Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Thiolutin suppresses tumor cell-induced...
Pyrocoll is a small secondary metabolite formed by the dimerisation of pyrrole-2-carboxylic acid and produced by many Streptomyces species. Pyrocoll is an important dereplication standard in discovery, displaying a highly distinctive UV spectrum. The...
Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin M contains a methyl group in the 8-position, and is less active than the vinyl analogue (gilvocarcin V), which is thought to...
Transplatin is the less-active isomer of the DNA damanging, platinum antitumor drug cisplatin, which is used in the treatment of a variety of solid tumors. However, it has been reported that the antitumor activity of transplatin can be photo-activated...
Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an...
Quinomycin A is a cyclic depsipeptide metabolite. Quinomycin A has broad activity against bacteria, fungi and viruses, and has found application as an antitumor agent. Quinomycin A acts by bifunctional intercalation of nucleic acids. Quinomycin A is an...
Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated...
Venturicidin B (Aabomycin A2) is a 20-member macrolide glycoside compound that was originally isolated from a Streptomyces sp.by Glaxo Labs in 1961. Venturicidin B is a potent antifungal and toxic antibiotic compound, that has also shown cytotoxicity to...
Trichostatin A is a histone deacetylase inhibitor that enhances the cytotoxic efficacy of anticancer drugs that target DNA. Trichostatin A displays antifungal, antiprotozoan and antitumor activity.Trichostatin A is soluble in ethanol, methanol, DMF, and...
