Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Thiostrepton, USP is a bactericidal macrocyclic thiopeptide antibiotic that is produced by Streptomyces azureus and was originally detailed by Donovick et al. in 1955. Thiostrepton shows broad...
LL Z1640-4 is a cis-enol resorcylic acid lactone first reported in 1978 exhibiting both antiviral and antiprotozoan activity. More recently, LL Z1640-2, containing the essential cis-enone system that...
Pirarubicin is an anthracycline anticancer agent, an analogue of doxirubicin that is able to overcome some doxirubicin resistant cell lines.TOKU-E offers both pirarubicin (P116) and pirarubicin...
Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective...
Zotarolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by preparation of the 42-triflate ester, followed by displacement with tetrazole and purification of the two isomeric...
Wortmannin is a steroidal metabolite belonging to the viridin group, isolated from Penicillium wortmannii in 1957. The structure was finally solved in 1968. Wortmannin exhibits broad spectrum...
L-Penicillamine is a metabolite of penicillin that acts as a copper chelating agent. TOKU-E offers both D-penicillamine (P107) and L-penicillamine (P112). While they are enantiomers of each other...
3-Anhydroophiobolin A is the dehydrated analogue of ophiobolin A and is a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus Bipolaris. Like all...
Trichostatin C is the first example of a glucopyranosyl hydroxamate from nature. The conjugation may act to protect the less stable N-OH group of Trichostatin A. Trichostatin C displays antifungal,...
Bestatin is 'pseudo'-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin also exhibits antitumor...
Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four...
Ridaforolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a dimethylphosphinate moiety. Ridaforolimus is extensively cited in...
