Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Norfloxacin is a first-generation synthetic fluoroquinolone antibiotic. Mechanism of Action Norfloxacin indirectly inhibits DNA gyrase by binding to nearby DNA substrate. DNA gyrase is an essential DNA replication enzyme which reduces DNA strain...
Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumor activity against several cell lines. Analogues of rebeccamycin have been tested in clinical trials for cancer therapy.Rebeccamycin...
Miconazole is an imidazole antimycotic compound patented in 1968 by Janssen Pharmaceutica. It inhibits ergosterol synthesis, and a variety of cytochrome P450 enzymes. It can act as a chemopreventive agent in a mammary cancer cell model...
7-Oxostaurosporine is the oxidised and highly fluorescent analogue of UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. 7-Oxostaurosporine possesses comparable...
Quinolactacin A1 is the dominant analogue of a family of quinolone metabolites produced by Penicillium citrinum. Quinolactacin A1 rapidly epimerises to equilibrate with its diastereomer quinolactacin A2 in protic solvents. The mixture has been shown to...
Stachybotrylactam is an unusual spirodihydrobenzofuranlactam mycotoxin isolated from a Stachybotrys sp. that has immunosuppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and...
Mitomycin C is a bacteriocidal methylazirinopyrroloindoledione antineoplastic antibiotic isolated from Streptomyces spp. Mitomycin C can be used as an inhibitor for cell-free protein biosynthesis research. In addition, Mitomycin C is an efficient...
Stauprimide is a semi-synthetic analogue of the staurosporine family of indolocarbazoles. Stauprimide was first published in 1994 as part of an extensive structure-activity investigation to improve the selective inhibition of protein kinase C as...
Cephalomannine is a diterpene alkaloid compound with antineoplastic properties. Cephalomannine is similar in structure to paclitaxel and can be used as a synthetic material for docetaxel and paclitaxel.Mechanism of ActionCephalomannine is thought to...
Carfilzomib is an anti-cancer tetrapeptide epoxyketone drug and is used for the treatment of multiple myeloma.Mechanism of ActionCarfilzomib prevents tumor growth by inhibiting 20S proteasome activity which leads to an accumulation of polyubiquinated...
Sulochrin is a fungal metabolite isolated from a number of Aspergillus and Penicillium sp.. An anti-angiogenic agent, sulochrin inhibits VEGF leading to inhibition of capillary-like tube formation of human umbilical vein endothelial cells. Sulochrin also...
Gentamicin ReadyMadeTM Solution is provided as a sterile-filtered solution of Gentamicin Sulfate formulated in water at a concentration of 50 mg/ml. It has been filter-sterilized using a 0.22 μm filter. Gentamicin Sulfate is routinely added to viral...
