Emodin is a tyrosine kinase inhibitor and is a natural anthraquinone derivative found in the roots and rhizomes of multiple plants. It has anti-inflammatory, antiviral, antibacterial and anticancer...
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl...
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active...
Mithramycin A was the first of the aureolic acid class of antitumor antibiotics, isolated from Streptomyces.Mithramycin A is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility...
Matrine is a natural alkaloid extracted from the Chinese herb Sophora flavescens. Matrine has demonstrated antiviral and anti-inflammatory bioactivity with relatively low toxicity. It has been used...
Meleagrin is an alkaloid with antitumor and antibiotic activity, isolated from a number of species of Penicillium. Meleagrin is a common taxonomic marker for fungal contamination of foodstuffs. Note...
Honokiol is a bioactive component of Magnolia obovata, known for its medicinal properties in traditional Asian medicine. Researchers have been interested in its antitumor activity, and have reported...
Kazusamycin B is a metabolite and minor member of the Leptomycin complex isolated from some Streptomyces species. It is a hydroxylated analog of Leptomycin A, a nuclear export inhibitor. It is...
Nogalamycin is an unusual anthracycline bacterial metabolite produced by Streptomyces nogalater var. nogalater reported by researchers at Upjohn in 1965. Nogalamycin contains two saccharides: the...
Neratinib Maleate is the maleate salt form of Neratinib. Neratinib is a quinoline derivative. It acts as a tyrosine kinase inhibitor and has anticancer properties. Neratinib has shown benefit for...
Neratinib is a quinoline derivative. It acts as a tyrosine kinase inhibitor and has anticancer properties. Neratinib has shown benefit for HER2 positive breast cancer and non-small cell lung cancer...
Tipiracil is a member of the pyrimidone class. It inhibits the enzyme thymidine phosphorylase (TPase), which is an endothelial cell growth factor. It is used in combination with Trifluidine, since...
