Antibacterials

Lincomycin

Lincomycin is a lincosamide first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial contains a rare amino acid (4-propyl-N-methylprolin) coupled to an equally rare aminomethylthio-octopyranoside sugar...

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Toxoflavin

Toxoflavin (PKF 118-310) is an azapteridine antibiotic produced by some species of Pseudomonas, Streptomyces, and Burkholderia gladioli that has antibiotic and anticancer properties.  It is also a yellow pigment that acts as a pH indicator changing...

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Rifampicin

Rifampicin (syn: Rifampin) is a semisynthetic antimicrobial compound derived from rifamycin SV and originally developed by the Lepetit group in 1965.  Rifampicin shows activity against Gram-positive bacteria, particularly mycobacteria like...

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Cetrimide

Cetrimide is a bactericidal cationic surfactant used against Gram-positive bacteria.  It is commonly used in selective media to isolate Pseudomonas aeruginosa. Cetrimide is an active ingredient in Cetavlon, a detergent used in plant surface...

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Sisomicin Sulfate

Sisomicin sulfate is a soluble broad-spectrum aminoglycoside antibiotic, and a dihydro analog of gentamicin C1a sulfate, Evopure.  Sisomicin was first isolated in 1970 from Micromonopora inyoensis, a novel strain at the time, that was...

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Sulfadiazine Sodium

Sulfadiazine sodium is a sulfonamide antibiotic that was developed in 1940 by Richard Roblin at the Stamford Research Laboratories of the American Cyanamid Company to be a more potent and less toxic alternative to Sulfapyridine. Sulfadiazine is a...

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Irgasan (Triclosan), USP

Irgasan, USP (syn: Triclosan, USP) is a broad spectrum antibacterial agent that inhibits bacterial fatty acid synthesis.   Irgasan is slightly soluble in water and freely soluble in ethanol and methanol. Mechanism of Action Irgasan...

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Teicoplanin

Teicoplanin (syn: Targocid, Teichomycin) is a lipoglycopeptide complex first reported from Actinoplanes teichomyceticus in 1978.  Teicoplanin is a mixture of several compounds including five major compounds (Teicoplanin A2-1 through A2-5), and four...

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Sulfadiazine

Sulfadiazine is a sulfonamide antibiotic that was developed in 1940 by Richard Roblin at the Stamford Research Laboratories (Stamford, Connecticut) of the American Cyanamid Company to be a more potent and less toxic alternative to Sulfapyridine...

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Vancomycin Hydrochloride, USP

Vancomycin Hydrochloride, USP (syn: Vancomycin HCl) is a glycopeptide antibiotic derived from Streptomyces orientalis that was discovered in 1953 from a soil sample found in Borneo. It is effective against Gram-positive bacteria such as...

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Novobiocin Sodium

Novobiocin Sodium is an aminocoumarin antibiotic that prevents cell division.  It is an inhibitor of Hsp90 can be used to study heat shock proteins.  It targets Gram-positive organisms, and is commonly used for antimicrobial susceptibility...

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Oxolinic Acid

Oxolinic acid is a synthetic quinolone antibiotic. It is insoluble in water and soluble in dilute alkali solutions. Mechanism of Action Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication...

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