Antibacterials

Sulbactam

Sulbactam is an irreversible inhibitor of several bacterial penicillinases and cephalosporinases. In the presence of low concentrations of sulbactam, ampicillin and other β-lactams readily inhibit the growth of a variety of resistant bacteria that...

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Terrecyclic Acid

Terrecyclic acid is a tricyclic sesquiterpene antibiotic produced by Aspergillus terreus, first reported by researchers at the Universities of Osaka and Tokyo in 1982. Terrecyclic acid A had a wide antimicrobial spectrum of rather weak activities...

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Sulbactam Sodium

Sulbactam Sodium is an irreversible inhibitor of several bacterial penicillinases and cephalosporinases. In the presence of low concentrations of sulbactam, ampicillin and other β-lactams readily inhibit the growth of a variety of resistant bacteria...

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Lincomycin

Lincomycin is a lincosamide first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial contains a rare amino acid (4-propyl-N-methylprolin) coupled to an equally rare aminomethylthio-octopyranoside sugar...

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Toxoflavin

Toxoflavin (PKF 118-310) is an azapteridine antibiotic produced by some species of Pseudomonas, Streptomyces, and Burkholderia gladioli that has antibiotic and anticancer properties.  It is also a yellow pigment that acts as a pH indicator changing...

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Rifampicin

Rifampicin (syn: Rifampin) is a semisynthetic antimicrobial compound derived from rifamycin SV and originally developed by the Lepetit group in 1965.  Rifampicin shows activity against Gram-positive bacteria, particularly mycobacteria like...

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Cetrimide

Cetrimide is a bactericidal cationic surfactant used against Gram-positive bacteria.  It is commonly used in selective media to isolate Pseudomonas aeruginosa. Cetrimide is an active ingredient in Cetavlon, a detergent used in plant surface...

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Sisomicin Sulfate

Sisomicin sulfate is a soluble broad-spectrum aminoglycoside antibiotic, and a dihydro analog of gentamicin C1a sulfate, Evopure.  Sisomicin was first isolated in 1970 from Micromonopora inyoensis, a novel strain at the time, that was...

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Sulfadiazine Sodium

Sulfadiazine Sodium is a sulfonamide antibiotic that was developed in 1940 by Richard Roblin at the Stamford Research Laboratories of the American Cyanamid Company to be a more potent and less toxic alternative to Sulfapyridine. Sulfadiazine is a...

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Irgasan (Triclosan)

Irgasan (syn: Triclosan) is a broad spectrum antibacterial agent that inhibits bacterial fatty acid synthesis.   Irgasan is slightly soluble in water and freely soluble in ethanol and methanol. Mechanism of Action Irgasan demonstrates a...

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Teicoplanin

Teicoplanin (syn: Targocid, Teichomycin) is a lipoglycopeptide complex first reported from Actinoplanes teichomyceticus in 1978.  Teicoplanin is a mixture of several compounds including five major compounds (Teicoplanin A2-1 through A2-5), and four...

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Sulfadiazine

Sulfadiazine is a sulfonamide antibiotic that was developed in 1940 by Richard Roblin at the Stamford Research Laboratories (Stamford, Connecticut) of the American Cyanamid Company to be a more potent and less toxic alternative to Sulfapyridine...

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