Antibacterials

Terbinafine Hydrochloride

Terbinafine Hydrochloride (Terbinafine HCl) belongs to the allylamine class of antifungals. It is active against fungi and yeast. It is used in studies of adsorption and stability. It is used against the dematophytic fungi. It has anti-cancer properties...

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Nalidixic Acid Sodium

Nalidixic Acid Sodium is a synthetic naphthyridone antibiotic developed by Sanofi Aventis. It is similar in structure and mechanism to quinolones, with a 1,8-naphthyridine nucleus containing 2 nitrogen atoms (unlike quinoline that contains a single...

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Ertapenem Sodium

Ertapenem Sodium is a broad-spectrum, β-lactam, a 1-beta-methyl carbapenem that interferes with peptidoglycan synthesis. Ertapenem has been commercially available since 2001 and is marked by Merck.  Ertapenem binds to penicillin binding...

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Cefuroxime Free Acid

Cefuroxime is a semi-synthetic, broad-spectrum, β-lactamase-resistant, second-generation cephalosporin. The compound was patented in 1971. It has increased stability to β-lactamases, which can widen the spectrum so that many organisms that are...

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Cefoperazone Sodium/Sulbactam Sodium (2:1)

Cefoperazone Sodium/Sulbactam Sodium (2:1) (Syn: Sulperazon) is a sterile homogeneous mixture of two parts Cefoperazone Sodium and one part Sulbactam Sodium by weight. It was developed in response to the β-lactamase challenge, due to the apperance...

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Cefoperazone Free Acid

Cefoperazone Free Acid is a semi-synthetic, broad-spectrum third-generation cephalosporin. Patented in 1974, it was marketed by Pfizer under the trade name Cefobid. The compound has activity against Pseudomonas. It has a tetrazolyl moiety that confers...

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WIN 66306

WIN 66306 is a cyclic peptide discovered during a search for inhibitors of Substance P binding to neurokinin (NK) receptors by Sterling Winthrop Pharmaceuticals in 1994. WIN 66306, isolated from Aspergillus sp., is active at both the NK1 and NK2 receptor...

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WF 3681

WF 3681 was isolated from Chaetomella sp. as a novel inhibitor of aldose reductase by researchers at Fujisawa Co. Japan in 1987, exhibiting an IC50 of 2.5 x 10-7 M. WF 3681 does not significantly reduce accumulation of sorbitol in rat sciatic nerves of...

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WEB 2086

WEB 2086 (apafant) is a potent and selective platelet activating (PAF) antagonist. WEB 2086 has high affinity for guinea pig peritoneal macrophage PAF receptors, dissociating slowly. WEB 2086 at 10-8 to 10-6 mol​/L strongly and...

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Turmerone

Turmerone is a non-polar 1,4-dialkylaryl metabolite isolated as a constituent of essential oil from turmeric (Curcuma longa), a plant with medicinal and culinary use. Turmerone has antimicrobial, insecticidal, larvicidal and antivenom properties against...

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Thaxtomin A

Thaxtomin A is a unique dioxopiperazine containing a 4-nitroindol-3-yl moiety isolated by scientists at Dow Agrisciences from Streptomyces scabies, the causative agent of common scab on new potatoes in 1989. Thaxtomin A is the predominant and most active...

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Syringic Acid

Syringic Acid, the 3,5-dimethyl ether derivative of gallic acid, is a phenolic compound found in fruits and vegetables which is synthesized via the shikimic acid pathway in plants. Syringic Acid has a broad bioprofile, having antioxidant,...

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