Antimycotics

Chlorhexidine

Chlorhexidine is an antiseptic antibacterial agent commonly used as a disinfectant in eye drops, deodorants, creams, and others. Chlorhexidine is also used as an active ingredient in mouthwash to prevent and control dental plaque.This product is...

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Pyrithione Sodium

Pyrithione Sodium (2-mercaptopyridine N-oxide) is a fungistatic and antimicrobial derivative of aspergillic acid.  It is a biocide with a broad spectrum of activity against fungi, Gram-positive and Gram-negative bacteria. Pyrithione has been used to...

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Caerulomycin

Caerulomycin is a rare and unusual antibiotic containing a core 2, 2'-bispyridyl with an oxime substituent, produced by a strain of Streptomyces caeruleus isolated in Canada in 1959. Caerulomycin is active against fungi and some protozoans, and is weakly...

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Aureothricin

Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Aureothricin is a more hydrophobic...

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Zotarolimus

Zotarolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by preparation of the 42-triflate ester, followed by displacement with tetrazole and purification of the two isomeric products. This structural change affords a less bioavailable...

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Wortmannin

Wortmannin is a steroidal metabolite belonging to the viridin group, isolated from Penicillium wortmannii in 1957. The structure was finally solved in 1968. Wortmannin exhibits broad spectrum antifungal activity, together with antitumor and...

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Anhydroophiobolin A

3-Anhydroophiobolin A is the dehydrated analogue of ophiobolin A and is a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus Bipolaris. Like all ophiobolins, 3-anhydroophiobolin A possesses a broad...

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Trichostatin C

Trichostatin C is the first example of a glucopyranosyl hydroxamate from nature. The conjugation may act to protect the less stable N-OH group of Trichostatin A. Trichostatin C displays antifungal, antiprotozoan and antitumor activity, albeit less potent...

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Blasticidin S

Blasticidin S is a peptidyl nucleoside produced by several species of Streptomyces that was first isolated from S. griseochromogenes in 1958.  Blasticidin S inhibits protein synthesis and is active against bacteria, fungi, nematodes, and tumor cells...

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Filipin

Filipin complex comprises a family of pentaene macrocyclic lactones first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Filipin complex consists of four analogues, with filipin III comprising the bulk (>70%) of...

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Ridaforolimus

Ridaforolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a dimethylphosphinate moiety. Ridaforolimus is extensively cited in the literature with over 70 citations.Ridaforolimus is...

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Cerulenin

Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens identified as an antifungal in the 1960s. Over the past 40 years, cerulenin has found broad application in lipid biochemistry as an inhibitor fatty acid and sterol...

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