Selective Agents

Novobiocin Sodium

Novobiocin Sodium is an aminocoumarin antibiotic that prevents cell division.  It is an inhibitor of Hsp90 can be used to study heat shock proteins.  It targets Gram-positive organisms, and is commonly used for antimicrobial susceptibility...

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Tetracycline, USP

Tetracycline, USP is a light-sensitive bacteriostatic polyketide antibiotic frequently used in a wide range of in-vitro cell culture applications. Tetracycline is a first-generation Tetracycline antibiotic and was first identified in 1953 by Chemist...

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Nystatin

Nystatin is a fungicidal and fungistatic polyene antifungal and growth promoter.  It functions by accumulating cholesterol and thereby sequesters lipid from cell membranes.  It can be used in quantum dot research, since cholesterol depletion...

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Oxolinic Acid

Oxolinic acid is a synthetic quinolone antibiotic. It is insoluble in water and soluble in dilute alkali solutions. Mechanism of Action Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication...

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Trimethoprim Lactate

Trimethoprim Lactate is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, Trimethoprim binds tightly to the bacterial enzyme, blocking...

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Trimethoprim

Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a dihydrofolate reductase inhibitor, trimethoprim binds tightly to the bacterial enzyme, blocking the production...

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Streptomycin Sulfate, EP

Streptomycin sulfate is a freely soluble aminocyclitol glycoside antibiotic, that was co-discovered by Salman Waksman, Albert Schatz, and Elizabeth Bugie at the Rutgers University in 1943 and was later patented in 1948.  Streptomycin is isolated...

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Fusidic Acid Sodium

Fusidic Acid Sodium is a bacteriostatic steroid triterpenoid antibiotic of the fusidane class which inhibits protein synthesis in Gram-positive bacteria.  It can be used to study the effects of compound combinations on bacterial growth, and gene...

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Methicillin Sodium

Methicillin Sodium is a narrow-spectrum β-lactam antibiotic belonging to the penicillin family and is a semi-synthetic derivative of penicillin.  It was manufactured in the late 1950s.  It is commonly used as a selective agent in pathogen...

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Vancomycin

Vancomycin is a glycopeptide antibiotic derived from Streptomyces orientalis that was discovered in 1953 from a soil sample found in Borneo. It is effective against gram-positive bacteria such as Staphylococcus aureus and is used in studies of...

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Norfloxacin

Norfloxacin is a first-generation synthetic fluoroquinolone antibiotic. Mechanism of Action Norfloxacin indirectly inhibits DNA gyrase by binding to nearby DNA substrate. DNA gyrase is an essential DNA replication enzyme which reduces DNA strain...

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Polymyxin B Sulfate, USP

Polymyxin B Sulfate, USP is a polypeptide antibiotic mixture composed of Polymyxins B1, B2, and B3 fractions, with B1 and B2 fractions comprising the majority of the mixture. Polymyxin B components are structurally identical with the exception of a...

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