Sinefungin, a polar nucleoside antifungal active with broad biological activity, was isolated from a number of species of Streptomyces in the early 1970s. Sinefungin is widely used as a bioprobe to block methyltransferase-dependent pathways.
Sinefungin is soluble in ethanol, methanol, DMF and DMSO.
Sinefungin is soluble in ethanol, methanol, DMF and DMSO.
| Mechanism of Action | Sinefungin acts by inhibiting a wide range of methyltransferases, including the methylation of bases in DNA and RNA which alters cytosine deamination and gene expression. |
| Molecular Formula | C15H23N7O5 |
