SKU: S107  / 
    CAS Number: 163253-35-8

    Sitafloxacin Hydrate


    Sitafloxacin Hydrate is a broad-spectrum fluoroquinoline antibiotic that is particularly active against Gram-positive bacteria such as a pneumococci.

    Mechanism of Action Sitafloxacin has been shown to have a dual targeted mechanism of action. Other antibacterial quinolones target DNA gyrase or topoisomerase IV, but sitafloxacin targets both at a very similar rate. This double-target approach lowers the possibility of resistant strains.
    Molecular Formula C19H18ClF2N3O3•  1.5H2O
    References Onodera, Y., Uchida, Y., Tanaka, M., & Sato, K. (1999). Dual inhibitory activity of sitafloxacin (DU-6859a) against DNA gyrase and topoisomeraseIV of Streptococcus pneumoniae. Journal Of Antimicrobial Chemotherapy, 44(4), 533-536.