Streptomycin, a metabolite of Streptomyces griseus, was first published as an antibiotic active against Gram-positive and Gram-negative bacteria by Schatz, Bugie and Waksman in 1944. Streptomycin was the first aminoglycoside antibiotic and first agent for tuberculosis. It was isolated by Albert Schatz in the laboratory of Selman Waksman (Rutgers) in a project funded by Merck and Co and Waksman was recognized with the Nobel Prize in Medicine for the discovery, with Albert Schatz also getting eventual recognition. It was the first aminoglycoside isolated from a bacterial source. After its discovery, several other aminoglyosides like Kanamycin, Neomycin and others were isolated from soil bacteria. Streptomycin is a bacterial protein synthesis inhibitor. Streptomycin is commonly used for bacterial gene selection and can be used as a selective agent in several types of isolation media.
Streptomycin is soluble in methanol or DMSO.
We also offer:
- Streptomycin Sulfate (S008)
- Streptomycin Sulfate, EP (S040)
- Streptomycin ReadyMadeTM Solution (S139)
- Streptomycin ReadyMadeTM EDTA Solution (S142)