Ternatin is a cyclic peptide antifungal metabolite, first isolated from the fungus Didymocladium ternatum in Russia in 1974. More recently, ternatin has been demonstrated to be a potent inhibitor of fat accumulation in 3T3-L1 murine adipocytes. Note that this metabolite should not be confused with the plant flavonoid of the same name.
Ternatin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.
Ternatin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.
| Molecular Formula | C37H67N7O8 |
| References | Convergent synthesis and in vivo inhibitory effect on fat accumulation of (−)-ternatin, a highly N-methylated cyclic peptide. Shimokawa K. et al. Bioorg. Med. Chem. Lett. 2005, 17, 4447. (−)-Ternatin, a highly N-methylated cyclic heptapeptide that inhibits fat accumulation: Structure and synthesis. Shimokawa K. et al. Tet. Lett. 2006, 47, 4445. |