Tilmicosin phosphate (20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin phosphate) is a salt of the semi-synthetic antibiotic derivative of desmycosin (tylosin B), a minor co-metabolite of tylosin, prepared by mixing the active tilmicosin with phosphoric acid to provide improved solubility and enhanced pharmacokinetics. Tilmicosin is a broad spectrum antibiotic, providing good protection against Pasteurella in livestock.
Tilmicosin phosphate is soluble in ethanol, methanol, DMF and DMSO.
Tilmicosin phosphate is soluble in ethanol, methanol, DMF and DMSO.
Molecular Formula | C46H83N2O17P |
References | Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (Tilmicosin, EL-870) and related cyclic amino derivatives. Debono M. et al. J. Antibiot. 1989, 42, 1253. |