SKU: T108  / 
    CAS Number: 14913-33-8

    Transplatin

    ₱8,905.17 - ₱27,773.55
    Transplatin is the less-active isomer of the DNA damanging, platinum antitumor drug cisplatin, which is used in the treatment of a variety of solid tumors. However, it has been reported that the antitumor activity of transplatin can be photo-activated. Several trans-platinum compounds have excellent anticancer bioactivity that overcomes cisplatin resistance, making transplatin an excellent starting place for the development of novel anticancer agents.
    ReferencesColuccia, M., & Natile, G. (2007). Trans-Platinum Complexes in Cancer Therapy. Anti-Cancer Agents in Medicinal Chemistry, 7(1), 111-123. doi:10.2174/187152007779314080

    Heringova, P., Woods, J., Mackay, F. S., Kasparkova, J., Sadler, P. J., & Brabec, V. (2006). Transplatin Is Cytotoxic When Photoactivated:  Enhanced Formation of DNA Cross-Links. Journal of Medicinal Chemistry, 49(26), 7792-7798. doi:10.1021/jm0606692