Tubermycin B (1-phenazinecarboxylic acid) is a simple phenazine produced by several species of Pseudomonas and Actinomycetes. Tubermycin B is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several Pseudomonas strains. Tubermycin B and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.
Tubermycin B is soluble in ethanol, methanol, DMF and DMSO.
Tubermycin B is soluble in ethanol, methanol, DMF and DMSO.
| Molecular Formula | C13H8N2O2 |
| References | Antibiotic substances produced by Pseudomonas aeruginosa. Hays E.E. et al. J. Biol. Chem. 1945, 159, 725. Biosynthesis and regulation of phenazine compounds in Pseudomonas spp. Mavrodi D.V. et al. in Pseudomonas, model organism, pathogen, cell factory. (B.H.A. Verlag GmbH & Co. Germany) 2009, 331. |
