Zearalanone (syn: ZAN) is a minor component of the zearalenone (syn: ZEN) complex produced by several species of Fusarium. Like the more abundant analogs, Zearalanone causes estrogenic effects in domestic livestock in vivo. Zearalanone is a mycoestrogen and F-2 toxin and metabolite of α-zearalanol, a commercial animal growth promotant and reference standard for detection of zearanol-contaminated products and Fusarium-contaminated grains.
Zearalanone is soluble in ethanol, methanol, DMF or DMSO. Zearalanone has limited water solubility.
We also offer:
- Zeralenone (syn: ZEN) (Z012)
| Plant Biology |
Zeralanone may be extracted from herbs via an immunoaffinity column. Fusarium graminearum is considered the primary source of Zearalanone. |
| References |
Faisal Z et al (2020) Interactions of zearalanone, α-zearalanol, β-zearalanol, zearalenone-14-sulfate, and zearalenone-14-glucoside with serum albumin. Mycotoxin Res 36:389–397 Matraszek-Zuchowska I, Wozniak B and Zmudzki J (2013) Determination of zeranol, taleranol, zearalanone, α-zearalenol, β-zearalenol and zearalenone in urine by LC-MS/MS. Food Additives & Contaminants: Part A, 30(6):987–994 Pompa G et al (1988) Zearanol metabolism by subcellular fractions from lamb liver. J. Vet. Pharmacol. Ther. 11:197 Steele JA et al (1976) Metabolism of Zearalenone by Fusarium roseum graminearum. J. Agr. Food Chem. 24:89 |