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Detailed Description
CAS Number: 56448-20-5
Molecular Formula: C20H30O7
Molecular Weight: 382.5
Tariff Code: 3822.00.5090
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Specifications
Form: Solid
Appearance: White solid
Source: Penicillium sp.
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Technical Data
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
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References
References:
Canova S et al (2011) Synthesis and biological properties of macrolactam analogs of the natural product macrolide (-)-A 26771B. Bioorg. Med. Chem. Lett. 21:4768
Michel KH (1977) The isolation and structure elucidation of macrocyclic lactone antibiotic.J. Antibiot. 30: 571
Stierle AA et al (2017) The berkeleylactones, antibiotic macrolides from fungal coculture. J. Nat. Products 80:1150
Tatsuta K et al (1980) Stereospecific total synthesis and absolute configuration of a macrocyclic lactone antibiotic, A26771B. Tetrahedron Letters 21:1479
A 26771B is a 16-membered macrocyclic lactone isolated from Penicillium turbatum patented and then published by Eli Lilly and Co. in 1975. A 26771B is closely related to the berkeleylactones, recently reported as antibiotics derived from a cofermentation of P. fuscum and P. camenbertii/clavigerum. A 26771B shows potent activity in vitro against Gram-positive bacteria and moderate activity against a broad selection of fungi. A 26771B inhibits potassium dependent ATPase in rat liver mitochondria.
CAS Number: 56448-20-5
Molecular Formula: C20H30O7
Molecular Weight: 382.5
Tariff Code: 3822.00.5090
Form: Solid
Appearance: White solid
Source: Penicillium sp.
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
References:
Canova S et al (2011) Synthesis and biological properties of macrolactam analogs of the natural product macrolide (-)-A 26771B. Bioorg. Med. Chem. Lett. 21:4768
Michel KH (1977) The isolation and structure elucidation of macrocyclic lactone antibiotic.J. Antibiot. 30: 571
Stierle AA et al (2017) The berkeleylactones, antibiotic macrolides from fungal coculture. J. Nat. Products 80:1150
Tatsuta K et al (1980) Stereospecific total synthesis and absolute configuration of a macrocyclic lactone antibiotic, A26771B. Tetrahedron Letters 21:1479