Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. More recently, aureothin has been shown to be a potent inhibitor of Helicobacter pylori.
Aureothin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.
Aureothin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.
| References | Gamma-pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M. et al. J Antibiot. 2000, 53, 844. Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Friedrich T. et al. Eur J Biochem. 1994, 219, 691. |
