SKU: A141  / 
    CAS Number: 13838-08-9

    Azidamfenicol

    Mex$3,706.50 - Mex$12,915.00
    Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide, first synthesised at Bayer in 1959. Azidamfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Azidamfenicol has received little research attention with only a few literature citations.

    Azidamfenicol is soluble in ethanol, methanol, DMF and DMSO.
    Mechanism of ActionAzidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis.
    Molecular FormulaC11H13N5O5
    References1-p-Nitrophenyl-2-azidoacetylaminopropane derivatives. Meiser W. & Domagk G. 1959 US Patent 2,882,275.