SKU: A081  / 
    CAS Number: 172617-84-4

    Azithromycin impurity I, EvoPure®


    Azithromycin impurity I, EvoPure® (3'-N-demethylazithromycin) is one of several impurities found in Azithromycin and can be used as a reference standard for impurity profiling.

    We also offer:

    • Azithromycin Impurity E, EvoPure® (A074)
    • Azithromycin Impurity F, EvoPure® (A075)
    • Azithromycin Impurity G, EvoPure® (A083)
    • Azithromycin impurity J, EvoPure® (A082)
    • Azithromycin impurity L, EvoPure® (A078)

    EvoPure® products have been fully characterized by spectral analysis and are shipped with a comprehensive certificate of analysis containing lot-specific HPLC, MS, HNMR, and FTIR data.

    Application Azithromycin impurity I is primarily used as a reference standard. Reference standards are well characterized compounds that can be used to help identify and/or quantify impurities in pharmaceutical compounds and antimicrobials.
    Molecular Formula C37H70N2O12

    Gladue RP, Bright GM, Isaacson RE, Newborg MF (1989) In vitro and in vivo uptake of Azithromycin (CP-62,993) by phagocytic cells: Possible mechanism of delivery and release at sites of infection. Antimicrob. Agents Chemother. 33(3):277-282 PMID 2543276

    Lovmar, M and Tenson T (2003) The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome."Journal of Molecular Microbiology 330 (5):1005-1014. PMID 12860123

    Wolf K and Malinverni R (1999) Effect of Azithromycin plus Rifampin versus that of Azithromycin alone on the eradication of Chlamydia pneumoniae from lung tissue in experimental pneumonitis. Antimicrob. Agents Chemother. 43(6):1491-1493. PMID 10348778