Butyrolactone II is one of a family of four butyrolactones isolated from the fungus, Aspergillus terreus, by Yamamoto and
collaborators at Kanazawa University, Japan in 1983. Butyrolactone II inhibits soybean lipoxygenase (LOX) and α-glucosidase. Butyrolactone II has antioxidant activity via DPPH radical-scavenging.
Dewi TR et al (2014) Effect on α-glucosidase inhibition and antioxidant activities of Butyrolactone derivatives from Aspergillus terreus MC751. Med. Chem. Res. 23:454
Nitta K et al (1983) Metabolic products of Aspergillus terreus. IX. Biosynthesis of Butyrolactone derivatives isolated from strains IFO 8835 and 4100. Chem. Pharm. Bull. 3:1528
Sugiyama Y et al (2010) Soybean lipoxygenase inhibitory and DPPH radical-scavenging activities of aspernolide A and Butyrolactones I and II. Biosci. Biotechnol. Biochem. 74:881