Cecropin B is an antimicrobial peptide originally isolated from insects, but now believed to be naturally produced and found in a large variety of organisms including mammals. It has garnered a lot of interest for its broad-spectrum antiparasitic and antibacterial activities. It is also active against fungi, and has cytotoxic effects on cancer cell lines.
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| Mechanism of Action | The antibacterial mode of action for Cecropins is pore-formation based, in which an antimicrobial peptide inserts itself into the bacterial membrane and allows ions to flow freely through, resulting in cell depolarization and death. |
| Molecular Formula | C176H301N51O42S |
| References | Chen, H. M., Wang, W., Smith, D., & Chan, S. C. (1997). Effects of the anti-bacterial peptide cecropin B and its analogs, cecropins B-1 and B-2, on liposomes, bacteria, and cancer cells. Biochimica Et Biophysica Acta (BBA) - General Subjects, 1336(2), 171-179. doi:10.1016/s0304-4165(97)00024-x |
