SKU: C237  / 
    CAS Number: 33075-00-2

    Cefathiamidine

    ₩239,926.50 - ₩778,140.00
    Cefathiamidine is a broad-spectrum first-generation cephalosporin β-lactam antibiotic.  It is used for the treatment of respiratory and urinary tract infections, pneumonia, sepsis, and meningitis.
    Mechanism of ActionLike β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.
    Microbiology ApplicationsCefathiamidine has a similar antibacterial spectrum as Cefalotin.
    Molecular FormulaC19H28N4O6S2
    ReferencesTze-Ying T et al (1979) Clinical and laboratory studies of a new cephalosporin derivative – cefathiamidine. Chin. Med. J. 92(1): 26-36 PMID 105842