SKU: C237  / 
    CAS Number: 33075-00-2

    Cefathiamidine

    S/.556.47 - S/.1,803.06
    Cefathiamidine
    • Detailed Description

      CAS Number: 33075-00-2

      Molecular Formula: C19H28N4O6S2

      Molecular Weight: 472.58

      Mechanism of Action: Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.

      Storage Conditions: -20C (hygroscopic)

    • Applications

      Spectrum: Gram-positive, Gram-negative

      Microbiology Applications: Cefathiamidine has a similar antibacterial spectrum as Cefalotin.

    • Specifications

      Form: Solid

      Appearance: White to off-white crystalline powder

      Source: Synthetic

      Purity Level: ≥97.0% (anhydrous basis)

    Cefathiamidine is a broad-spectrum first-generation cephalosporin β-lactam antibiotic.  It is used for the treatment of respiratory and urinary tract infections, pneumonia, sepsis, and meningitis.

    CAS Number: 33075-00-2

    Molecular Formula: C19H28N4O6S2

    Molecular Weight: 472.58

    Mechanism of Action: Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.

    Storage Conditions: -20C (hygroscopic)

    Spectrum: Gram-positive, Gram-negative

    Microbiology Applications: Cefathiamidine has a similar antibacterial spectrum as Cefalotin.

    Form: Solid

    Appearance: White to off-white crystalline powder

    Source: Synthetic

    Purity Level: ≥97.0% (anhydrous basis)