Chlorhexidine is an antibacterial agent commonly used disinfective agent and has broad-spectrum activity. Chlorhexidine is used in dental research studies as it is a common additive to prevent dental plaque.
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| Mechanism of Action | Chlorhexidine is a cationic molecule which interacts with and alters the negatively charged bacterial cell wall. This interaction leads to leakage of cellular components at low concentrations and cellular lysis at higher concentrations. |
| Spectrum | Chlorhexidine has a broad spectrum of activity and is active against Gram-positive and Gram-negative bacteria as well as yeasts and some viruses. |
| Molecular Formula | C22H30Cl2N10 |
| References | Jones, Christopher G. "Chlorhexidine: Is It Still the Gold Standard." Periodontology 15 (1997): 55-62. |
