Deoxygerfelin was isolated from a mutagen-treated strain of Aspergillus fumigatus that failed to produce fumigatin and
spinulosin, by researchers at Kanazawa University, Japan in 1972. Deoxygerfelin is closely related to gerfelin, a metabolite isolated from Beaveria felina as a geranylgeranyl diphosphatate synthase inhibitor. The biological profile of Deoxygerfelin is largely unexplored.
| Molecular Formula | C15H14O5 |
| References | Yamamoto et al (1972) Metabolic products of a strain of Aspergillus fumigatus DH 413. V. New metabolite produced by ethionine inhibition. Yamamoto Y. et al., Chem. Pharm. Bull. 1972, 20, 931. Zenitani S et al (2003) Gerfelin, a novel inhibitor of geranylgeranyl diphosphate synthase from Beauveria felina QN22047. I. Taxonomy, fermentation, isolation, and biological activities. J. Antibiot. 56: 617 |