Erythromycin A 9-oxime is a semi-synthetic analog Erythromycin prepared as means of overcoming acid lability and improving oral absorption of Erythromycin A while retaining antibacterial potency. Although not developed as a commercial product, Erythromycin Oxime was pivotal in the development of the ring expanded aza-erythromycins (e.g. azithromycin) and the oxime ethers (e.g. roxithromycin).
Erythromycin A 9-oxime is soluble in water, ethanol, methanol, DMF and DMSO.
Erythromycin A 9-oxime is soluble in water, ethanol, methanol, DMF and DMSO.
For other Erythromycin products, click here.
| References | Gasc JC et al (1994) New ether oxime derivative of erythromycin A structure-activity relationship study. J. Antibiot. 44: 313 Djokic SJ (1986) Erythromycin series. Part 11. Ring expansion of erythromycin A oxime by the Beckmann rearrangement. Chem. Soc. Perkin Trans.: 1881 |
