Kanamycin Sulfate ReadyMadeTM solution is provided as a sterile-filtered solution of Kanamycin Sulfate formulated in 0.9% NaCl at a concentration of 10 mg/ml. It has been filter-sterilized using a 0.22 μm filter.
Kanamycin Sulfate is a semi-synthetic, broad-spectrum aminoglycoside antibiotic. Kanamycin was isolated from the soil bacterium Streptomyces kanamyceticus in 1957 by Hamao Umezawa at the institute of Microbial Chemistry (Tokyo) during an antitumor screening program using the transplanted Yoshida sarcoma in mice. Kanamycin inhibits protein synthesis in bacteria and Mycoplasma. It is used to select for transformants (bacteria, fungi, plant, mammalian) which have been successfully transformed with a plasmid containing a kanamycin-resistance gene.
Standard-grade Kanamycin is composed of 3 fractions: Kanamycin A, B, and C, with Kanamycin A being the major component.
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