Lactoferricin B is a broad-spectrum antimicrobial peptide (AMP) that is generated by the enzymatic digestion of lactoferrin. Lactoferricin B is derived from bovine lactoferrin. Lactoferricin B has activity against gram-positive and gram-negative bacteria, yeasts and filamentous fungi. It has shown immunomodulatory activity and antitumor activity.
|Mechanism of Action||The mechanism of action of Lactoferricin B is not yet fully confirmed, however it has been shown to attack the bacterial membrane causing leakage of the cytoplasm.|
|References||Moniruzzaman, M., Alam, J. M., Dohra, H., & Yamazaki, M. (2015). Antimicrobial peptide Lactoferricin b-induced rapid leakage of internal contents from single giant Unilamellar Vesicles. Biochemistry, 54(38), 5802–5814. doi:10.1021/acs.biochem.5b00594|