Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi.
Ophiobolin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Ophiobolin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
| Mechanism of Action | Ophiobolin A acts by inhibiting calmodulin action in calcium regulation. |
| References | Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis. Quetglas S. EMBO J. 2002, 21, 3970. The biology of ophiobolins. Au T.K. et al. Life Sci. 2000, 67, 733. (Review) |
