SKU: O022  / 
    CAS Number: 4611-05-6

    Ophiobolin A

    R$1,317.20 - R$4,610.14
    Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi.

    Ophiobolin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
    Mechanism of ActionOphiobolin A acts by inhibiting calmodulin action in calcium regulation.
    ReferencesCalmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis. Quetglas S. EMBO J. 2002, 21, 3970.

    The biology of ophiobolins. Au T.K. et al. Life Sci. 2000, 67, 733. (Review)