Ristocetin A sulfate is a potent antibacterial glycopeptide antibiotic that was withdrawn from clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease, leading to the use of ristocetin A as an important diagnostic aid.
Ristocetin A sulfate is soluble in ethanol, methanol, DMF and DMSO.
Ristocetin A sulfate is soluble in ethanol, methanol, DMF and DMSO.
Molecular Formula | C95H112N8O48S |
References | Ristocetin A and B, two new antibiotics. Isolation and properties. Philip J.E. et al. Antibiot. Annu. 1955, 699. Ristocetin - a new tool in the investigation of platelet aggregation. Howard M.A. et al. Throm. Diath. Haemorrh. 1971, 26, 362. |