Bioactive small molecules are organic compounds that have a low molecular weight (900 daltons). Most pharmaceutical drugs are small molecules. Larger structures such as nucleic acids, proteins, and many polysaccharides are not small molecules.
Flomoxef Free Acid (syn: Flomoxef) is a β-lactam antibiotic, an oxa-1 cephamycin belonging to the oxacephem group. It has broad-spectrum activity against Gram-negative and Gram-positive bacteria...
Secnidazole is a second-generation 5-nitroimidazole antibiotic and analog of metronidazole. It has in vitro activity against anaerobic bacteria and can be used in research for trichomoniasis,...
Vaborbactam is a non-β-lactam β-lactamase inhibitor. It is synthetic biochemical based on a a cyclic boronic acid pharmacophore. It was discovered by Rempex Pharmaceuticals, a subsidiary of The...
Ozenoxacin is a quinolone antibiotic with bacterididal activity against Staphylococcus aureus and Streptococcus pyogenes, the causal agents of impetigo. Ozenoxacin also has activity against some...
Dihydroartemisinin (syn: DHA) is a first-generation derivative of artemisinin, isolated from Artemisia annua, a traditional Chinese herb. It is the major metabolite of artemether, an antimalarial...
Zidebactam is a non-β-lactam antibiotic that is categorized as a diabicyclooctane (DBO). It is a penicillin-binding protein 2 (PBP2) inhibitor with a high affinity for PBP2 in Gram-negative bacteria...
Trovafloxacin Mesylate is a broad-spectrum fluoroquinolone antibiotic. It was developed for immunology research (Pfizer). It can inhibit both Gram-positive and Gram-negative bacteria, and anaerobic...
Ravuconazole is a triazole antifungal, a 1-butyl-1H-1,2,4- triazole. The compound has a broad-spectrum antifungal activity, and is active against molds and yeast. It has a spectrum similar to...
Efinaconazole is a triazole antifungal and 14α-demethylase inhibitor. The compound was synthesized as an azoleamine derivative (Kaken Phermaceutical Co). The fungal lanosterol 14α-demethylase is...
Geldanamycin ReadyMadeTM solution is provided as a sterile-filtered solution of Geldanamycin formulated in DMSO at a concentration of 1 mg/ml. It has been filter-sterilized using a 0.22 μm filter...
Amicoumacin B is a complex antibiotic and isocoumarin produced by Bacillus subtilis. This natural product, a fungal metabolite, is a quorum-sensing inhibitor with activity against Chromobacterium...
Lecanoric acid is an orcinol depside found in a broad range of lichen and fungal species. Structurally, lecanoric acid is a dimer of orsellinic acid. Lecanoric acid is a broad antimicrobial agent,...
