Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Chaetocin is an epithiodioxopiperazine antibiotic that has recently shown promise as a selective antitumor agent. Chaetocin is dramatically accumulated in cancer cells via a process inhibited by glutathione. Inside the cell, its activity is mediated by...
Menadione (Vitamin K3) is the precursor to vitamin K2 in mammals. It has also been tested as a possible anticancer agent able to induce apoptosis. Menadione is suitable for microbiology use. We also offer: Menadione sodium bisulfite...
Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor active...
Albofungin is a polyaromatic heterocycle containing a rare N-aminoamide, isolated from a Streptomyces species in Russia in 1959. Albofungin exhibits a broad biological profile with antibiotic, antifungal, anthelmintic and very potent antitumor activity...
Doxorubicin (syn: Adriamycin) is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for use as an antitumor agent for a wide range...
Cytochalasin J is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, which give rise to pronounced morphogenic activity in animals and plants. Cytochalasin J is...
Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene (IC50 = 11 ng/ml). Apoptolidin is among the most selective cytotoxic agents tested by the NCI in human...
Epiequisetin is a minor isomer of equisetin, a potent inhibitor of HIV-integrase produced by a number of species of Fusarium. Chemically, equisetin equilibrates with epiequisetin. Although found to have comparable phytotoxicity to equisetin, epiequisetin...
Cercosporamide was originally identified as a host-selective phytotoxin and broad spectrum antifungal agent isolated from Cercosporidium henningsii.Cercosporamide is soluble in ethanol, methanol, DMF and DMSO.Mechanism of ActionCercosporamide was...
Dihydrocyclosporin A is co-metabolite of Cyclosporin A. Dihydrocyclosporin A has no immunosuppressant activity and has found use as a control to determine the role of Cyclosporin A in pharmacology, particularly for parasitic infections...
Setomimycin is a rare 9,9'-bianthryl antibiotic first isolated from a strain of Streptomyces pseudovenezuelae by Omura and colleagues at the Kitasato Institute, Japan, in 1978. Setomimycin is active against Gram positive bacteria, including mycobacteria,...
Bafilomycin A1 is a member of a potent family of macrocyclic lactones with broad spectrum biological activity, including activity against bacteria, yeast, fungi, nematodes, insects and tumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type...
