Our products for cancer research include natural products, antibiotics, chemotherapeutic agents, anti-tumor agents, drug precursors, and immunosuppressants. There are hundreds of high quality compounds to choose from to further your discoveries.
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Caffeic acid phenethyl ester is a natural phenolic compound from honeybee hives and has demonstrated anti-carcinogenic, anti-bacterial, and antiinflammatory properties.Mechanism of ActionCaffeic acid phenethyl ester inhibits bacterial growth by the...
Calphostin C (PKF115-584) is a perylenequinione isolated from the fungus, Cladosporium cladosporioides and inhibits cell proliferation and induces apoptosis in vitro.Calphostin C is soluble in ethanol, methanol, DMF and DMSO.Mechanism of...
Δ2-Ivermectin B1a is an irreversible base degradation product of ivermectin found in animals treated with ivermectin and in the environment. Δ2-Ivermectin B1a is formed by rearrangement of the naturally occurring Δ3-group to the 2-position. Despite the...
Isocyclosporin A is a rearranged degradation product formed by acid treatment of Cyclosporin A under aqueous and non-aqueous conditions. This rearrangement has been used as the basis of a HPLC fluorescence for quantifying Cyclosporin A. The pharmacology...
Metformin is a common first line antidiabetic drug, and the only FDA approved member of the biguanide drug class. More recently it has drawn attention from the cancer research sector. Several clinical trials for the use of metformin in the treatment of...
Lenalidomide is an analogue of the immunomodulatory drug thalidomide with increased potency and fewer adverse effects. It is used in the treatment of hematologic and solid cancers due to its antitumor and anti-angiogenic activities.Mechanism of...
Neochlorogenic acid is a natural polyphenol compound found primarily in fruits. Other polyphenols have proven to have a wide array of bioactivity, and already neochlorogenic acid has demonstrated anti-inflammatory activity.Mechanism of ActionResearchers...
Neoaureothin is an unusual chain-extended analogue of aureothin. Neoaureothin was first reported as a co-metabolite of neoantimycin in Streptomyces orinoci. Neoaureothin has anti-HIV and antifungal activity. Recent investigations have identified two...
Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. Chartreusin is also a potent inhibitor of topoisomerase II.Chartreusin is soluble ethanol, methanol, DMF and DMSO.Mechanism of...
LL Z1640-2 (5Z-7-oxozeaenol) is a cis-enone resorcylic acid lactone first reported in 1978 and later rediscovered as an irreversible and highly selective TAK 1 inhibitor. TAK1 is a MAPKKK involved in the p38 signalling cascade for pro-inflammation...
Antimycin A1 is the most hydrophobic of the four analogs of the Antimycin A complex. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes.Antimycin...
Anhydroepiophiobolin A is a dehydrated analogue of ophiobolin epimerised at the C6 position. Anhydroepiophiobolin A is the major terminal degradation product of ophiobolin A and is co-produced with other ophiobolins in many Bipolaris species. Prior to...
