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TS155-2 is a macrocyclic lactone related to hygrolidin but produced by a different Streptomyces species. With the exception of the original patent suggesting hypotensive, anti-platelet,...
UK-1 is an unusual bis-benzoxazole metabolite isolated from a species of Streptomyces. UK-1 exhibits good antitumor activity but is devoid of antimicrobial activity.Mechanism of ActionUK-1 acts as a...
Umirolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group, providing one of most hydrophobic tacrolimus analogues. Umirolimus has been...
Valinomycin is a hydrophobic cyclodepsipeptide with potent antitumor activity. Valinomycin is a highly selective potassium ionophore and this action leads to a diverse range of profound cell membrane...
Moxalactam Sodium (syn: Latamoxef Sodium) is a an oxacephem antibiotic usually grouped with the cephalosporins. In oxacephems such as these, the sulfur atom of the cephalosporin core is replaced with...
Nicotinamide (Vitamin B3), USP is water-soluble amide form of Nicotinic acid. It is a poly (ADP-ribose) polymerase (PARP) inhibitor, involved in regulation of many cellular processes. It was...
Erythromycin is a broad-spectrum macrolide antibiotic derived from Saccharopolyspora erythraea (formerly Streptomyces erythraeus) that inhibits bacterial protein synthesis. It is composed largely of...
Cordycepin (syn: 3'-deoxyadenosine) is a derivative of the nucleoside adenosine which differs from adenosine in that the hydroxy group in the 3' position is replaced with hydrogen. It was originally...
Hyaluronic Acid Sodium is the sodium salt form of Hyaluronic acid, an anionic anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is...
Cisplatin (syn: cis-diammineplatinum(II) dichloride; cis-[Pt(NH3)2Cl2), is a potent anti-tumor agent and is active against several types of solid tumors. It is a square planer coordination complex of...
Apigenin (from Matricaria recutita) is a natural occurring, ubiquitous, low molecular weight plant flavone with low toxicity and is the most bioactive of the plant flavones. It belongs to the...
Hydrocortisone, USP (syn: Cortisol) is a glucocorticoid steroid hormone produced in the adrenal cortex. It can be used as a supplement in culture medium for oligodendrocytes, colon cells, and...