Icotinib is an anticancer agent. Icotinib acts as an inhibitor of mutated, overactive or overexpresssed epidermal growth factor receptor (EGFR). Because epidermal growth factors are responsible for...
Dacarbazine is an alkylating antineoplastic agent, a chemotherapy compound used in the research of numerous cancers including melanoma and Hodgkin's lymphoma. It was first synthesized at Southern...
Icaritin is a hydrolytic product of icariin, and one of the bioactive components of the epimedium genus. It has gained interest mainly from its anticancer activity, including its ability to slow the...
Acalabrutinib is a highly selective, irreversible inhibitor of Bruton's tyrosine kinase (BTK), and is being considered for use in the treatment of relapsed chronic lymphoid leukemia. Mutations in BTK...
Hydroxyurea is an antineoplastic chemotherapeutic compound used in sickle cell anemia studies and cancer research, including leukemia, skin cancer, and ovarian cancers.Hydroxyurea is freely soluble...
Ingenol-3-mebutate is an anticancer agent isolated from Euphorbia peplus used in the treatment of Actinic keratosis. Researchers have shown interest in expanding its anticancer activity, finding...
Etoposide is an anticancer topoisomerase inhibitor and semisynthetic epipodophyllotoxin that was derived from the natural product podophyllotoxin extracted from the North American mayapple,...
Dabrafenib is a selective inhibitor of BRAF, a proto-oncogene. It is primarily used for cancer research to study melanoma. Mechanism of Action Dabrafenib is a reversible and potent adenosine...
Dasatinib is multitarget kinase inhibitor used in the treatment of leukemia. Dasatinib's main targets are tyrosine kinase BCR/ABL, which works to provide the cancer cell with ATP at an uncontrolled...
Imatinib Mesylate is a tyrosine kinase inhibitor used primarily in cancer research studies focused on leukemia. Chronic Myeloid Leukemia (CML) cells contain a hybrid tyrosine kinase BCR/ABL that...
Oligomycin A is a dominant analog of the Oligomycin class of macrocyclic lactones isolated from selected strains of Streptomyces sp. The class includes the analogs/isomers A through G. Different...
Oligomycin B is a minor analog of a class of macrocyclic lactones isolated from selected strains of Streptomyces spp. It is a non-selective inhibitor of mitochondrial F1F0 ATP synthase in eukaryotes...
