Antimicrobials

Cefiderocol

Cefiderocol is a siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain.  It has in vitro activity against the non-fermenting Gram-negative bacteria causing urinary tract infections. It is a siderophore conjugate...

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Remdesivir

Remdesivir is a broad-spectrum antiviral developed by Gilead Sciences. Remdesivir is a prodrug, and upon entry into cells, it is metabolized into the nuceotide triphosphate GS-441524. Remdesivir was investigated for activity for Ebola virus, but it was...

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Baloxavir Marboxil

Baloxavir Marboxil is a synthetic antiviral compound. It has activity against viruses causing influenza A and influenza B. It originated by Shionogi (Japan). It is a small molecule inhibitor of cap-dependent endonuclease found in of influenza A and B...

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Sulfachloropyridazine Sodium

Sulfachloropyridazine Sodium is the sodium salt of Sulfachloropyridazine, a sulfonamide antibiotic. It has been used to treat the bacteria causing urinary tract infections and is commonly used in aquaculture and animal husbandry. Sulfachloropyridazine...

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Pretomanid

Pretomanid is a bicyclic nitroimidazole and small molecule pro-drug that is active against actively replicating and hypoxic non-replicating Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). It is activated by deazaflavin-dependent...

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Echinocandin B Nucleus Hydrochloride

Echinocandin B Hydrochloride is the hydrochloride salt of a the natural product and lipopeptide antifungal Ehinocandin B. Discovered in 1974 in Germany, it is the first of its class of antifungals called echinocandins. Echinocandin B is a cyclic...

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Pyrantel Citrate

Pyrantel Citrate is a thiophene and anthelmintic agent. It has been used to characterize Ancylostoma caninum isolates. It was described in 1965 by researchers at Pfizer. Pyrantel and its analogs (oxantel and morantel) are members of the...

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Fosfomycin Calcium

Fosfomycin Calcium is a broad-spectrum phosphonic acid epoxide antibiotic that inhibits bacterial cell wall synthesis.  It is used against bacteria causing urinary tract and intestinal infections and is commonly used in susceptibility testing. ...

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4-Epitetracycline Ammonium Salt, EvoPure®

4-Epitetracycline ammonium salt, EvoPure® is a highly purified version of 4-Epitetracycline, an epimer of Tetracycline. Tetracycline is a broad-spectrum antibacterial and selection agent. We also offer:4-Epitetracycline Hydrochloride, EvoPure®...

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4'-Acetylchrysomycin A

4’-Acetylchrysomycin A and its co-metabolite, 4’-acetylchrysomycin B, were isolated during a screen for antitumor agents. Acetylation of chyrsomycin A reduces cytotoxicity, although both are highly potent (IC50s 64 μg ml-1 for...

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Alphitonin

Alphitonin is a flavonoid-related metabolite related to quercetin isolated from the heartwood of the Australian red ash, Alphitonia excela in 1922. Alphitonin's structure was reported by Birch and Ritchie in 1960. Alphitonin is thermally and enzymically...

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Asperuloside

Asperuloside is an iridoid monoterpenoid glycoside derived from the Rubiaceae family of flowering plants first reported in 1893.  More recently, Asperuloside was reported to have been efficiently isolated from Coprosma quadrifida via rapid...

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