Antimicrobials

Lachnone A

Lachnone A is a chromone isolated from the filamentous fungus Lachnum sp. in 2006, along with known (2E,6S)-2,6-dimethyl-2,7-octadiene-1,6-diol. Lachnone A possesses weak activity against bacteria but has not been extensively investigated.Lachnone A is...

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Cysteamine hydrochloride

Cysteamine is a compound used in the study of cystine transport disorders in humans. More recently it has gained interest as an antibiofilm compound, particularly for cystic fibrosis research.Cysteamine Hydrochloride is very soluble in water and alcohol...

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Nitrofurantoin Sodium

Nitrofurantoin Sodium is the sodium salt of Nitrofurantoin, a broad-spectrum nitrofuran antibiotic that is used as a substrate for bacterial glycoprotein nitrofuran reductase. It is bacteriostatic against Gram-positive and Gram-negative bacteria. The...

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Framycetin Sulfate

Framycetin Sulfate (syn: Neomycin B Sulfate) is the sulfate salt form of Neomycin, a broad-spectrum aminoglycoside antibiotic derived from Streptomyces fradiae.  Neomycin B is ~ 65% more active than its stereoisomer, Neomycin C, and ~ 90% more...

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Extracellular Death Factor

Extracellular Death Factor (EDF) is the dramatic name given to an interesting linear pentapeptide produced by E. coli, first identified by Engelberg-Kulka and colleagues in 2007 and published in Science.EDF is soluble in ethanol, methanol, DMF or DMSO...

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Erythromycin C

Erythromycin C (3''-O-demethylerythromycin) is a minor co-metabolite of Erythromycin.  Other metabolites include A, B, and D   Erythromycin C exhibits a narrower spectrum of antibiotic activity and is less active than A and B. ...

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Erythromycin A oxime

Erythromycin A 9-oxime is a semi-synthetic analog Erythromycin prepared as means of overcoming acid lability and improving oral absorption of Erythromycin A while retaining antibacterial potency. Although not developed as a commercial product,...

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Erythromycin A N-oxide

Erythromycin A N-oxide is a minor analog of the Erythromycin complex.  The N-oxide is a facile metabolite formed in vivo which can revert to Erythromycin A under reducing conditions. Despite its synthetic preparation in the 1950s, the biological...

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Flomoxef Sodium

Flomoxef Sodium is a β-lactam inhibitor and member of the oxacephem family and exhibits antibiotic properties.  It has been used for respiratory infections and bone diseases (ie osteoporosis).  It was synthesized in 1982 by Shionogi &...

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4-Epichlortetracycline Hydrochloride

Epichlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. Epichlortetracycline exhibits little antibiotic activity but its abundance is indicative of poor storage and...

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4-Epianhydrochlortetracycline Hydrochloride

4-Epianhydrochlortetracycline Hydrochloride (chlortetracycline impurity K) is a secondary degradation product formed by dehydration of epichlortetracycline at the C6 position to aromatise the B ring. 4-Epianhydrochlortetracycline is an important standard...

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Temocillin Disodium

Temocillin Disodium is the salt of Temocillin, a semisynthetic, β-­lactamase-resistant carboxypenicillin antimicrobial. Temocillin is the 6-alpha-methoxy derivative of ticarcillin.  Temocillin is is used as an alternative to carbapenems and...

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