Antimicrobials

Aflatoxin B2

Aflatoxin B2 is the minor analogue of the blue fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Aflatoxins are one of the most potent mycotoxins known but are in fact 'pre-toxins', requiring metabolic...

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Aflatoxin B1

Aflatoxin B1 is the major analogue of a family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Aflatoxin B1 exhibits a distinctive UV spectrum and blue fluorescence. Aflatoxins are among the most potent mycotoxins...

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Fidaxomicin

Fidaxomicin is the major analog of a family of macrocyclic lactones, isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3,...

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Dihydrotanshinone I

Dihydrotanshinone I is one of many bioactive products isolated from Salvia miltiorrhiza, a well-known traditional Chinese medicinal plant. It's primary promise lies in its anticancer activity, but it has been found to be active against gram-positive...

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Berninamycin A

Berninamycin A is an antibiotic discovered in 1976 from a strain of Streptomyces. Berninamycin A is a macrocyclic 'peptide' comprising atypical amino acids linked to thiazole and oxazoles. Berninamycin A is closely related to siomycin, a recently...

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Berninamycin D

Berninamycin D is an antibiotic isolated in 1994 from a strain of Streptomyces as a minor analogue of berninamycin A. Berninamycin D is a macrocyclic 'peptide' comprising atypical amino acids linked to thiazole and oxazoles but does not contain the...

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Corynecin III

Corynecin III (methamphenicol) is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin III is active against Gram positive and Gram negative...

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Dalbavancin

Dalbavancin is a semi-synthetic glycopeptide prepared from A40926 by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in...

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Nalidixic Acid Sodium, CulturePure®

Nalidixic Acid Sodium, CulturePure® is a synthetic 1,8-naphthyridone antibiotic similar in structure and mechanism to quinolones, the commercial preparation of which was developed by Sanofi Aventis.  The product is commonly used as a selective...

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Dalfopristin Mesylate

Dalfopristin is a semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulfone. The structural...

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Decatromicin B

Decatromicin B is a tetronic acid isolated from a strain of Actinomadura in 1999. Decatromicin B is a potent antibiotic with activity against antibiotic sensitive and resistant strains such as MRSA. Lack of availability has hampered further investigation...

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Aspartocin D

Aspartocin D is a minor analogue of the amphomycin complex, a family of lipopeptide antibiotics produced by Streptomyces canus, isolated and reported by researchers at Fujian Institute of Microbiology in China in 2014. Aspartocin D is active against Gram...

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