Aquastatin A, produced by Fusarium sp., is an inhibitor of mammalian adenosine triphosphatases with an IC50 of 7.1 µM against Na+/K+-ATPase 6.2 µM against H+/K+-ATPase. Aquastatin A is a potent...
Apramycin is a structurally unique broad-spectrum aminoglycoside with a bicyclic sugar moiety and a monosubstituted deoxystreptamineactive. Apramycin inhibits the translocation step of bacterial...
Ansamitocins, a new group of ansamycin antibiotics with potent antitumor activity, were first reported in the journal Nature in 1977 by researchers from Takeda Chemical Industries. Anisomitocin P3 is...
Anandamide is an endogenous ligand for the cannabinoid receptor. Anandamide activates receptor-mediated signal transduction and stimulates arachidonic acid and intracellular calcium release in both...
Anagyrine is a teratogenic quinolizidine alkaloid found in Lupinus sp. which undergoes metabolism to a piperidine that causes crooked calf syndrome. Anagyrine, but not lupanine or sparteine, directly...
Amycolatopsin C is a glycosylated polyketide isolated by Microbial Screening Technologies from Amycolotopsis sp.. The amycolatopsins are closely related to the ammocidins and apoptolidins...
Amycolatopsin B is a glycosylated polyketide isolated by Microbial Screening Technologies. The amycolatopsins are closely related to the ammocidins and apoptolidins. Amycolatopsin A and C, bearing a...
Amycolatopsin A is a glycosylated polyketide isolated by Microbial Screening Technologies from Amycolotopsis sp. The amycolatopsins are closely related to the ammocidins and apoptolidins...
Aminopterin is a 4-amino derivative of folic acid and a folic acid antagonist. It is a synthetic derivative of pterin. It has both mmunosuppressive properties and anti-cancer properties and can be...
Ambuic acid is an antifungal cyclohexanone metabolite produced by Pestalotiopsis sp. Ambuic acid inhibits the biosynthesis of quorum sensing peptides in Gram-positive bacteria. Ambuic acid may exert...
Alternariol monomethylether was first reported by Raistrick and colleagues in 1953. Alternariol and its monomethyl ether analogue occur in mycelium of Alternaria tenuis responsible for alternaria...
Actinonin is a metabolite of Streptomyces roseoplallidus and other Streptomyces species, first reported in Nature in 1962. Actinonin is a bacteriostatic agent with activity against Gram-positive and...
