Antibacterials

Tobramycin Sulfate, USP

Tobramycin Sulfate, USP is an aminoglycoside antibiotic derived from Streptomyces tenebrarius. Tobramycin is a member of a broad-spectrum antibiotic complex, nebramycin, that was originally isolated in 1967 by Eli Lilly and Company.  The nebramycin...

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Trimethoprim Lactate

Trimethoprim Lactate is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, Trimethoprim binds tightly to the bacterial enzyme, blocking...

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Trimethoprim

Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with bacteriostatic and antiprotozoal properties. As a dihydrofolate reductase inhibitor, trimethoprim binds tightly to the bacterial enzyme, blocking the production...

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Fusidic Acid Sodium

Fusidic Acid Sodium is a bacteriostatic steroid triterpenoid antibiotic of the fusidane class which inhibits protein synthesis in Gram-positive bacteria.  It can be used to study the effects of compound combinations on bacterial growth, and gene...

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Methicillin Sodium

Methicillin Sodium is a narrow-spectrum β-lactam antibiotic belonging to the penicillin family and is a semi-synthetic derivative of penicillin.  It was manufactured in the late 1950s.  It is commonly used as a selective agent in pathogen...

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Vancomycin

Vancomycin is a glycopeptide antibiotic derived from Streptomyces orientalis that was discovered in 1953 from a soil sample found in Borneo. It is effective against gram-positive bacteria such as Staphylococcus aureus and is used in studies of...

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Norfloxacin

Norfloxacin is a first-generation synthetic fluoroquinolone antibiotic. Mechanism of Action Norfloxacin indirectly inhibits DNA gyrase by binding to nearby DNA substrate. DNA gyrase is an essential DNA replication enzyme which reduces DNA strain...

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Polymyxin B Sulfate, USP

Polymyxin B Sulfate, USP is a polypeptide antibiotic mixture composed of Polymyxins B1, B2, and B3 fractions, with B1 and B2 fractions comprising the majority of the mixture. Polymyxin B components are structurally identical with the exception of a...

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Nalidixic Acid

Nalidixic Acid is a synthetic 1,8-naphthyridone antibiotic similar in structure and mechanism to quinolones.  It can be used as a tool to study bacterial division regulation.  The compound can also be used in the RADAR assay, a method for...

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Lincomycin Hydrochloride, USP

Lincomycin Hydrochloride is the hydrochloride form of Lincomycin, provided as the monohydrate. Lincomycin is a naturally occurring lincosamide isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. This class of antibacterial contains a...

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Fosfomycin Sodium

Fosfomycin Sodium is broad-spectrum phosphoenolpyruvate analog antibiotic.  It has a chemically unique structure unlike any other antibacterial agent.  Fosfomycin has been found to have an immunomodulatory effect on human B-cell activation...

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Ceftazidime Pentahydrate

Ceftazidime Pentahydrate is a broad-spectrum, third-generation, β-lactam cephalosporin that interferes with bacterial cell wall synthesis.  Patented in 1979 by Glaxo Group, Ceftazidime came into commercial use in 1984.  Ceftazidime is...

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