Carbazomycin D is a minor analogue of a family of carbazoles initially isolated from Streptomyces ehimense reported by researchers at Hiroshima University in 1987. Carbazomycin D was identified in a scaled and optimised fermentation of the same strain...
Molecular Formula C16H17NO3
Carbazomycin B is the dominant analogue of a family of rare carbazoles initially isolated from an unidentified Streptomyces sp. by researchers at Hiroshima University in 1980. Carbazomycin B is a 5-lipoxygenase inhibitor and free radical scavenger...
Carbazomycin A is a minor metabolite of a family of rare carbazoles initially isolated from an unidentified Streptomyces sp. (subsequently identified as Streptomyces ehimense) by researchers at Hiroshima University in 1980. Carbazomycin A is active...
Simvastatin acid is the active β-hydroxy acid metabolite of simvastatin formed in vivo. Simvastatin acid is a potent inhibitor of 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase, an essential enzyme involved in the in vivo synthesis of...
Molecular Formula C23H30N2O4
Burnettramic acid A and its aglycone are members of a new class of antibiotics from an Australian fungus Aspergillus burnettii. The rare bolaamphiphilic scaffold consists of β-d-mannose linked to a pyrrolizidinedione unit via a 26-carbon...
Molecular Formula C5H8N2O2
Beauveriolides are 13-membered cyclodepsipeptides isolated from Beauveria sp. Beauveriolide III inhibits acyl-CoA:cholesterol acyltransferase (ACAT) to block the synthesis of cholesteryl ester, leading to a reduction of lipid droplets in macrophages...
Beauveriolides are 13-membered cyclodepsipeptides isolated from Beauveria sp.. Beauveriolides I and III inhibit macrophage acyl-CoA:cholesterol acyltransferase (ACAT) activity to block the synthesis of cholesteryl ester, leading to a reduction of lipid...
Beauvericin A, a cyclic depsipeptide isolated from serveral fungal genera, notably Fusarium and Beaveria, is the methyl analogue of beauvericin. Beauvericin A is active against mycobacterium and plasmodia. Molecular...
