Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the...
Aphidicolin is a tetracyclic diterpene antibiotic isolated from fungi, notably Cephalosporium, Nigrospora, Harziella and Phoma. Aphidicolin has antibiotic, antiviral and antimitotic properties,...
Nigericin is a polyether antibiotic produced by Streptomyces, notably S. hygroscopicus, isolated in the 1950s. Its complex structure was finally elucidated in 1968. Although Nigericin can be isolated...
TAN 420C is a minor analogue of the herbimycin complex, isolated from Streptomyces hygroscopicus. TAN 420C is the hydroquinone of herbimycin C, and is known to exhibit antitumor activity. TAN 420C...
Narasin sodium is prepared from narasin taking advantage of the carboxylic acid which ionises and readily forms the salt in sodium hydroxide solutions. Narasin is an ionophore with broad spectrum...
Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidal antibiotic, also exhibiting antifungal and antiviral...
Toxoflavin (PKF 118-310) is an azapteridine antibiotic produced by some species of Pseudomonas, Streptomyces, and Burkholderia gladioli that has antibiotic and anticancer properties. It is also a...
Fumagillin is a polyene natural product and mycotoxin isolated from Aspergillus fumigatus in 1951 as a potent antiprotozoan for agents that cause amoebiasis. More recently, Fumagillin has been shown...
Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on...
Cercosporin (CGP049090) is a perylenequinone reported in 1957 as the causative agent of soy bean purple speck disease due to the fungal pathogen, Cercsopsorium kikuchii, which is widely found in...
Ascochlorin is an antitumor fungal metabolite with antitumor and antiviral properties.Ascochlorin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility.Mechanism of...
LL Z1640-4 is a cis-enol resorcylic acid lactone first reported in 1978 exhibiting both antiviral and antiprotozoan activity. More recently, LL Z1640-2, containing the essential cis-enone system that...
